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1

The improved synthesis, Diels-Alder reactions, and desulfuration of trithio-1,8-naphthalic anhydride

Tian-Bao Huang, Xuhong Qian, Zhi-Fu Tao, Ke Wang, Gong-Hua Song, Ling-Fei Liu

Journal:

Heteroatom Chemistry

Year:

1999

Language:

english

File:

PDF, 174 KB

english, 1999

2

Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors

Gaoquan Li, Lisa A. Hasvold, Zhi-Fu Tao, Gary T. Wang, Stephen L. Gwaltney II, Jyoti Patel, Peter Kovar, Robert B. Credo, Zehan Chen, Haiying Zhang, Chang Park, Hing L. Sham, Thomas Sowin, Saul H. Ros

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

3

Synthesis of naphthopyrones as potential monofunctional photobiological agents to DNA

Zhi-Fu Tao, Xuhong Qian

Journal:

Dyes and Pigments

Year:

1998

Language:

english

File:

PDF, 214 KB

english, 1998

4

Design, Synthesis, and Biological Activity of 5,10-Dihydro-dibenzo[ b , e ][1,4]diazepin-11-one-Based Potent and Selective Chk-1 Inhibitors

Wang, Le, Sullivan, Gerard M., Hexamer, Laura A., Hasvold, Lisa A., Thalji, Reema, Przytulinska, Magdalena, Tao, Zhi-Fu, Li, Gaoquan, Chen, Zehan, Xiao, Zhan, Gu, Wen-Zhen, Xue, John, Bui, Mai-Ha, Mer

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 411 KB

english, 2007

5

Solid-Phase Synthesis of Bleomycin A 5 and Three Monosaccharide Analogues: Exploring the Role of the Carbohydrate Moiety in RNA Cleavage

Thomas, Craig J., Chizhov, Alexander O., Leitheiser, Christopher J., Rishel, Michael J., Konishi, Kazuhide, Tao, Zhi-Fu, Hecht, Sidney M.

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 68 KB

english, 2002

6

SYNTHESIS OF 2H-4,8-DIMETHYLTHIENO[2′,3′: 5,6]NAPHTHO[1,2-b]PYRAN-2-ONE WITH POTENTIAL PHOTOBIOLOGICAL ACTIVITY TO DNA

Tao, Zhi-Fu, Qian, Xuhong

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Year:

1996

Language:

english

File:

PDF, 337 KB

english, 1996

7

Heat transfer and flow of a dense suspension between two cylinders

Wu, Wei-Tao, Zhou, Zhi-Fu, Aubry, Nadine, Antaki, James F., Massoudi, Mehrdad

Journal:

International Journal of Heat and Mass Transfer

Year:

2017

Language:

english

File:

PDF, 2.41 MB

english, 2017

8

Sequenzspezifische DNA-Alkylierung durch Hybridmoleküle aus Segment A von Duocarmycin A und einem Pyrrol-Imidazol-Diamid

Zhi-Fu Tao, Tsuyoshi Fujiwara, Isao Saito, Hiroshi Sugiyama

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 137 KB

german, 1999

9

Sequence-Specific DNA Alkylation by Hybrid Molecules between Segment A of Duocarmycin A and Pyrrole/Imidazole Diamide

Zhi-Fu Tao, Tsuyoshi Fujiwara, Isao Saito, Hiroshi Sugiyama

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 153 KB

english, 1999

10

ChemInform Abstract: Sequence-Specific DNA Alkylation by Hybrid Molecules Between Segment A of Duocarmycin A and Pyrrole/Imidazole Diamide.

Zhi-Fu Tao, Tsuyoshi Fujiwara, Isao Saito, Hiroshi Sugiyama

Journal:

Year:

1999

File:

PDF, 25 KB

1999

11

ChemInform Abstract: The Improved Synthesis, Diels—Alder Reactions, and Desulfuration of Trithio-1,8-naphthalic Anhydride.

Tian-Bao Huang, Xuhong Qian, Zhi-Fu Tao, Ke Wang, Gong-Hua Song, Ling-Fei Liu

Journal:

Year:

1999

File:

PDF, 35 KB

1999

12

ChemInform Abstract: Synthesis of Novel DNA-Intercalating Naphthopyrone Derivatives with Improved Water Solubility and Photophysical Properties.

Zhi-Fu Tao, Mingcai Fan, Xuhong Qian

Journal:

Year:

1999

File:

PDF, 31 KB

1999

13

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

Zehan Chen, Zhan Xiao, Wen-zhen Gu, John Xue, Mai H. Bui, Peter Kovar, Gaoquan Li, Gary Wang, Zhi-Fu Tao, Yunsong Tong, Nan-Horng Lin, Hing L. Sham, Jean Y. J. Wang, Thomas J. Sowin, Saul H. Rosenberg

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 1.69 MB

english, 2006

14

Synthesis of furonaphthalimides as novel DNA intercalators

Zhi-Fu Tao, Xuhong Qian, Jun Tang

Journal:

Dyes and Pigments

Year:

1996

Language:

english

File:

PDF, 269 KB

english, 1996

15

1,8-Naphthalimide hydroperoxides as novel intercalating DNA cleavers

Zhi-Fu Tao, Xuhong Qian, Dongzhi Wei

Journal:

Dyes and Pigments

Year:

1996

Language:

english

File:

PDF, 309 KB

english, 1996

16

Synthesis and characterization of the linear MHgM trimetallic complexes [η5-Bz5C5(CO3M]2Hg and [η5-HO2CC5H4(CO3M]2Hg(M = Cr, Mo, W). The X-ray crystal structure of η5-Bz5C5(CO)3W]2Hg

Li-Cheng Song, Lu-Yan Zhang, Zhi-Fu Tao, Qing-Mei Hu, Xiao-Ying Huang

Journal:

Year:

1997

Language:

english

File:

PDF, 434 KB

english, 1997

17

Solid-phase synthesis and biochemical evaluation of conformationally constrained analogues of deglycobleomycin A5

Ali Cagir, Zhi-Fu Tao, Steven J Sucheck, Sidney M Hecht

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 378 KB

english, 2003

18

1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Extended exploration on phenyl ring substitutions and preliminary ADME/PK studies

Yunsong Tong, Akiyo Claiborne, Magdalena Pyzytulinska, Zhi-Fu Tao, Kent D. Stewart, Peter Kovar, Zehan Chen, Robert B. Credo, Ran Guan, Philip J. Merta, Haiying Zhang, Jennifer Bouska, Elizabeth A. Ev

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

19

Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors

Zhi-Fu Tao, Gaoquan Li, Yunsong Tong, Zehan Chen, Philip Merta, Peter Kovar, Haiying Zhang, Saul H. Rosenberg, Hing L. Sham, Thomas J. Sowin, Nan-Horng Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 443 KB

english, 2007

20

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability

Yunsong Tong, Magdalena Przytulinska, Zhi-Fu Tao, Jennifer Bouska, Kent D. Stewart, Chang Park, Gaoquan Li, Akiyo Claiborne, Peter Kovar, Zehan Chen, Philip J. Merta, Mai-Ha Bui, Amanda Olson, Donald

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

21

Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors

Zhi-Fu Tao, Gaoquan Li, Yunsong Tong, Kent D. Stewart, Zehan Chen, Mai-Ha Bui, Philip Merta, Chang Park, Peter Kovar, Haiying Zhang, Hing L. Sham, Saul H. Rosenberg, Thomas J. Sowin, Nan-Horng Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 330 KB

english, 2007

22

Macrocyclic ureas as potent and selective Chk1 inhibitors: An improved synthesis, kinome profiling, structure–activity relationships, and preliminary pharmacokinetics

Zhi-Fu Tao, Zehan Chen, Mai-Ha Bui, Peter Kovar, Eric Johnson, Jennifer Bouska, Haiying Zhang, Saul Rosenberg, Thomas Sowin, Nan-Horng Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 304 KB

english, 2007

23

Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors

Gaoquan Li, Zhi-Fu Tao, Yunsong Tong, Magdalena K. Przytulinska, Peter Kovar, Philip Merta, Zehan Chen, Haiying Zhang, Thomas Sowin, Saul H. Rosenberg, Nan-Horng Lin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 181 KB

english, 2007

24

A facile synthesis of antitumoral indeno[1,2-c]pyrazole-4-one by mild oxidation with molecular oxygen

Zhi-Fu Tao, Thomas J. Sowin, Nan-Horng Lin

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 105 KB

english, 2005

25

Naphthalimide hydroperoxides as photonucleases: substituent effects and structural basis

Zhi-Fu Tao, Xuhong Qian

Journal:

Dyes and Pigments

Year:

1999

Language:

english

File:

PDF, 154 KB

english, 1999

26

Synthesis and characterization of trimetallic complexes [η5-RC5H4(CO)3E]2Hg (E = Cr, Mo, W ; R = Me, Et, n-Bu). Crystal structure of [η5-EtC5H4(CO)3Cr]2Hg

Li-Cheng Song, Zhi-Fu Tao, Qing-Mei Hu, Ru-Ji Wang, Hong-Gen Wang

Journal:

Year:

1994

Language:

english

File:

PDF, 546 KB

english, 1994

27

Sequence Specificity, Reactivity, and Antitumor Activity of DNA-Alkylating Pyrrole-Imidazole Diamides

Toshikazu Bando, Hirokazu Iida, Zhi-Fu Tao, Akihiko Narita, Noboru Fukuda, Takao Yamori, Hiroshi Sugiyama

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 1.01 MB

english, 2003

28

Synthesis, crystal structure, and properties of 2H-4,8-dimethylfuro[2′,3′:5,6]naphtho[1,2-b]pyran-2-one, a novel DNA intercalator

Xuhong Qian, Zhi-Fu Tao, Dongzhi Wei, Jie Sun

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

1996

Language:

english

File:

PDF, 497 KB

english, 1996

29

Synthesis of NovelDNA-Intercalating Naphthopyrone Derivatives with Improved Water Solubility and Photophysical Properties

Zhi-Fu Tao, Mingcai Fan, Xuhong Qian

Journal:

Monatshefte für Chemie - Chemical Monthly

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

30

Signal transduction during cold, salt, and drought stresses in plants

Guo-Tao Huang, Shi-Liang Ma, Li-Ping Bai, Li Zhang, Hui Ma, Ping Jia, Jun Liu, Ming Zhong, Zhi-Fu Guo

Journal:

Molecular Biology Reports

Year:

2012

Language:

english

File:

PDF, 550 KB

english, 2012

31

Regioselective synthesis and photooxygenations of furonaphthopyrones starting from 2,7-naphthalenediol

Zhi-Fu Tao, Xuhong Qian, Mingcai Fan

Journal:

Year:

1997

Language:

english

File:

PDF, 547 KB

english, 1997

32

Synthesis of 3H-1,8,9-trimethylthieno[3′,2′:6,7]naphtho [2,1-b]pyran-3-one with potential photobiological activity

Zhi-Fu Tao, Xuhong Qian, Yinbi Zhang, Mingcai Fan

Journal:

Dyes and Pigments

Year:

1998

Language:

english

File:

PDF, 120 KB

english, 1998

33

Synthesis and DNA Cleavage Activity of a Novel Bleomycin A 5 Glycoconjugate

Choudhury, Ambar K., Tao, Zhi-Fu, Hecht, Sidney M.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 90 KB

english, 2001

34

Discovery of 3 H -Benzo[4,5]thieno[3,2- d ]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases

Tao, Zhi-Fu, Hasvold, Lisa A., Leverson, Joel D., Han, Edward K., Guan, Ran, Johnson, Eric F., Stoll, Vincent S., Stewart, Kent D., Stamper, Geoff, Soni, Nirupama, Bouska, Jennifer J., Luo, Yan, Sowin

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.89 MB

english, 2009

35

Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors

Tao, Zhi-Fu, Wang, Le, Stewart, Kent D., Chen, Zehan, Gu, Wendy, Bui, Mai-Ha, Merta, Philip, Zhang, Haiying, Kovar, Peter, Johnson, Eric, Park, Chang, Judge, Russell, Rosenberg, Saul, Sowin, Thomas, L

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 463 KB

english, 2007

36

Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: A potential role for reducing UVB light-induced retinal damage

Li, Chao-Peng, Yao, Jin, Tao, Zhi-Fu, Li, Xiu-Miao, Jiang, Qin, Yan, Biao

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

37

Modulation of Sequence Specificity of Duocarmycin-Dependent DNA Alkylation by Pyrrole−Imidazole Triamides

Fujiwara, Tsuyoshi, Tao, Zhi-Fu, Ozeki, Yohei, Saito, Isao, Wang, H.-J., Lee, Moses, Sugiyama, Hiroshi

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 80 KB

english, 1999

38

Rational Design of Sequence-Specific DNA Alkylating Agents Based on Duocarmycin A and Pyrrole−Imidazole Hairpin Polyamides

Tao, Zhi-Fu, Fujiwara, Tsuyoshi, Saito, Isao, Sugiyama, Hiroshi

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 153 KB

english, 1999

39

Discovery of a Potent and Selective BCL-X L Inhibitor with in Vivo Activity

Tao, Zhi-Fu, Hasvold, Lisa, Wang, Le, Wang, Xilu, Petros, Andrew M., Park, Chang H., Boghaert, Erwin R., Catron, Nathaniel D., Chen, Jun, Colman, Peter M., Czabotar, Peter E., Deshayes, Kurt, Fairbrot

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.57 MB

english, 2014

40

Solid-Phase Synthesis of Deglycobleomycins: A C-Terminal Tetraamine Linker That Permits Direct Evaluation of Resin-Bound Bleomycins

Tao, Zhi-Fu, Leitheiser, Christopher J., Smith, Kenneth L., Hashimoto, Shigeki, Hecht, Sidney M.

Journal:

Bioconjugate Chemistry

Year:

2002

Language:

english

File:

PDF, 317 KB

english, 2002

41

Alteration of the Selectivity of DNA Cleavage by a Deglycobleomycin Analogue Containing a Trithiazole Moiety

Thomas, Craig J., McCormick, Michael M., Vialas, Corine, Tao, Zhi-Fu, Leitheiser, Christopher J., Rishel, Michael J., Wu, Xihan, Hecht, Sidney M.

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 167 KB

english, 2002

42

Conformationally Constrained Analogues of Bleomycin A 5

Rishel, Michael J., Thomas, Craig J., Tao, Zhi-Fu, Vialas, Corine, Leitheiser, Christopher J., Hecht, Sidney M.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 287 KB

english, 2003

43

An Efficient Mammalian Transfer RNA Target for Bleomycin

Tao, Zhi-Fu, Konishi, Kazuhide, Keith, Gérard, Hecht, Sidney M.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 102 KB

english, 2006

44

Highly Cooperative DNA Dialkylation by the Homodimer of Imidazole−Pyrrole Diamide−CPI Conjugate with Vinyl Linker

Tao, Zhi-Fu, Saito, Isao, Sugiyama, Hiroshi

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 451 KB

english, 2000

45

Deglycobleomycin: Solid-Phase Synthesis and DNA Cleavage by the Resin-Bound Ligand

Smith, Kenneth L., Tao, Zhi-Fu, Hashimoto, Shigeki, Leitheiser, Christopher J., Wu, Xihan, Hecht, Sidney M.

Journal:

Organic Letters

Year:

2002

Language:

english

File:

PDF, 125 KB

english, 2002

46

Epigenetics and Ocular Diseases: From Basic Biology to Clinical Study

Yan, Biao, Yao, Jin, Tao, Zhi-Fu, Jiang, Qin

Journal:

Journal of Cellular Physiology

Year:

2014

Language:

english

File:

PDF, 995 KB

english, 2014

47

Impact on L-carnitine Homeostasis of Short-term Treatment with the Pivalate Prodrug Tenofovir Dipivoxil

Jia, Yan-Yan, Lu, Cheng-Tao, Feng, Juan, Song, Ying, Zhao, Jin-Yi, Wang, Shan, Sun, Yuan, Wen, Ai-Dong, Yang, Zhi-Fu, Hang, Tai-Jun

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2013

Language:

english

File:

PDF, 114 KB

english, 2013

48

lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNANovelty and Significance

Yan, Biao, Yao, Jin, Liu, Jing-Yu, Li, Xiu-Miao, Wang, Xiao-Qun, Li, Yu-Jie, Tao, Zhi-Fu, Song, Yu-Chen, Chen, Qi, Jiang, Qin

Journal:

Circulation Research

Year:

2015

Language:

english

File:

PDF, 3.21 MB

english, 2015

49

Long noncoding RNAs: versatile players in biologcial processes and human disorders

Yan, Biao, Wang, Zhen-Hua, Liu, Jing-Yu, Tao, Zhi-Fu, Li, Xiu-Miao, Qin, Jiang

Journal:

Year:

2014

Language:

english

File:

PDF, 792 KB

english, 2014

50

Dynamic imaging of autophagy-lysosomal pathway and autophagy function following pulmonary hypoxia/reoxygenationin vitro

Liu, Tian-shu, Cai, Yi-ting, Mao, Zhi-fu, Huang, Jie, Fan, Tao, Geng, Qing

Journal:

Journal of Huazhong University of Science and Technology -- Medical Sciences --

Year:

2015

Language:

english

File:

PDF, 3.44 MB

english, 2015